The ſame malignant ſpotted Fever, which firſt appeared in Europe in 1505, prevailed now again with its malignant contagious Conſtitution, from the ſame Cauſe ; for the laſt Winter was wholly rainy and ſoutherly. The Spring the ſame, with very great and deſtructive Inundations, Darkneſs and Fogs, which killed the Buds of Trees, eſpecially the Olives. This Fever begun ſo mildly, that the Sick ſcarce perceived themſelves ill, or in need of a Phyſician before it was too late. Nor were Phyſicians themſelves leſs deceived, expecting a ſpeedy Criſis, but no ſuch thing. The Heat was not ſenſibly great, but the inward great Perturbation of the whole Body was manifeſt from its general and great Laſſitude, Dullneſs of the Senſes, ſupine lying in Bed, and heavy Headyneſs of the Sick. After the 4th or 7th Day they began to talk wildly ; their Eyes were red and fiery. The Urine was firſt plentiful and whitiſh, then red and turbid ; Pulſe low and ſlow ; Excrements corrupt and fetid. On the 4th or 7th Day, little red Spots like Flea-bites began to appear on the Back, Arms, and Breaſt. Very little or no Thirſt ; the Tongue was foul. Some were watchful, others very ſleepy, and ſome both in their Turns ; ſome continued in this Condition to the 7th or 14th Day, or longer. Some had a Stoppage of Urine, which was a bad Sign. No Jews died of it. Some few Women and old People died of it ; but it made ſad havock of Children and Youth, and thoſe of the richer ſort chiefly. All had a ſudden and great Loſs of Strength. A ſmall Laxative made a great Diſcharge. No Mitigation from a Criſis, great Loſs of Blood at the Noſe, difficult Eruption ſuddenly diſappearing, a livid Colour of the Spots, or a Stoppage of Urine, were all bad Signs ; and the contrary were good. Great and fatal was the Diſſention, of Phyſicians about the Cure ; ſome were for bleeding of all freel y; but others ſtrictly obſerving tht all that were Blood of died, would let none. Others took the middle Way, and ordered Blood-letting ſparingly at firſt, of plethoric or ſanguine People only ; and ſo about other Evacuations and Diet. But the beſt Method was a middling Diet, and boiled Water given to drink, or Water with a little Vinegar, or with Cinnamon, and a little Syrup of Wood Sorrel. They kept the Air in the Rooms of the Sick, clear and good ; or perfumed by burning Herbs and Gums. After the ſecond Day none were let Blood, but were cupped, or had the Saphena, or Hemorrhoidal Veins opened. Where the Body was full of groſs Humours, they gave Caſſia, Manna, or Syrup of pale Roſes, or with Agaric. About the Eruption, of the Puſtules came out ſlowly, they gave Scordium, Trifol. Odorat. but no ſtrong Sudorifics. They uſed powerful Diuretics. All hot Things given, added to the Fever, encreaſed its Danger and bad Symptoms.